This manual addresses the clinical management of the transplant patient from pre surgical evaluation through the peri operative period and into the recovery and follow up phases of care each major transplant organ is covered with a common chapter structure covering recipient evaluation donor evaluation surgical procedure post operative . Immune reconstitution following organ transplantation is absolutely critical in preventing infectious complications however understanding the kinetics of immune reconstitution and its potential impact on the clinical management of transplant patients remains a significant challenge. Solid organ transplantation is a well recognized and common therapy for many end stage diseases the medical care of patients undergoing transplant is developing into a discrete speciality involving input from critical care physicians anaesthesiologists and a variety of clinicians from both medical and surgical specialities. Kidney transplantation is associated with improvement in quality of life and mortality as compared to remaining on dialysis it is therefore the optimal treatment for kidney failure for most patients while transplantation nephrologists typically care for the patient in the first 6 months posttransplantation general nephrologists and internists often care for kidney transplant recipients . Precise fluid management will help prevent pulmonary oedema oxygen therapy will be weaned as the patients clinical condition allows fluid balance renal function the assessment and management of a patients fluid balance following heart transplant can be challenging
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