Amazoncom bioengineering aspects of the lung lung biology in health and disease volume 3 9780824763787 john b west books skip to main content try prime en hello sign in account lists sign in account lists returns orders try prime cart books go search . However due to the small tidal volume breaths the patients lung has a large proportion of dead space and reduced alveolar minute ventilation with less co 2 clearance the majority of hfov studies treated neonatal patients and reported small reductions in chronic lung disease . Additionally cortiella et al mention the importance of both substrate properties and 3 d structure for lung bioengineering how the mechanical properties of the substrate modulate stem cell fate is currently subjected to intense research focusing on both substrate stiffness and 3 d architecture 35 39. Applying biotechnology and bioengineering to pediatric lung disease emerging paradigms and platforms the study of lung disease continues to be transformed by biotechnology and bioengineering biologically inspired technologies will undoubtedly continue to yield key insights into the structural and mechanical aspects of lung biology that . Bioengineering a functional vascularized lung scaffold new approach to bioengineering lungs selectively treats epithelium that lines the lung airway while preserving lung vasculature
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